|
Vol. 11.28 – 20 July, 2022
|
|
|
|
|
|
Using genetic mouse mammary tumor and human breast cancer models, researchers showed that the histone reader ZMYND8 was selectively expressed in breast CSCs (BCSCs) and promoted epithelial-mesenchymal transition, BCSC maintenance and self-renewal, and oncogenic transformation through its epigenetic functions, leading to breast tumor initiation. [Science Advances]
|
|
|
|
|
PUBLICATIONSRanked by the impact factor of the journal
|
|
|
|
|
Investigators demonstrated that β2-microglobulin promoted maintenance of stem-like neoplastic populations and reprogramed the tumor immune microenvironment to an anti-inflammatory, tumor-promoting state.
[Cancer Research]
|
|
|
|
|
The authors investigated the role of CSCs in angiogenesis and hypoxic response in oral squamous cell carcinoma.
[BMC Oral Health]
|
|
|
|
|
The expression of Frrizled receptor 7 in pancreatic ductal adenocarcinoma and relating survival rate were analyzed by bioinformatics, histochemistry assay and follow-up study.
[Molecular Medicine]
|
|
|
|
|
Scientists mapped the development of mouse cerebrum across the developmental time-course, from embryonic day 12.5 to postnatal day 365, performing single-cell transcriptomics on over 100,000 cells.
[Nature Communications]
|
|
|
|
|
The authors explored the potential targets and molecular mechanisms of honokiol on metastatic breast CSC-cell cycle arrest and the impact of the tumor microenvironment.
[Evidence-Based Complementary and Alternative Medicine]
|
|
|
|
|
circRNAs differentially expressed in esophageal squamous cell carcinoma and adjacent normal tissues were characterized via high-throughput sequencing.
[Journal of Translational Medicine]
|
|
|
|
|
Researchers showed that lysosomal protein transmembrane 5 promoted lung-specific metastasis in renal cancer.
[Nature Communications]
|
|
|
|
|
Investigators analyzed copy-number alterations of selected genes in our cohorts of CSCs and in The Cancer Genome Atlas cohort with the aim to correlate their frequency with patients’ prognosis. [World Journal of Urology]
|
|
|
|
|
|
|
Scientists review the most relevant interactions carried out between the stem cells, tumor cells and immune cells in a bottom-up incursion through the tumor microenvironment beginning from the perivascular niche and going through the tumoral parenchyma and the related stroma. [Stem Cell Reviews and Reports]
|
|
|
|
|
|
Ohio State University investigations identified misconduct by two scientists in lab of high-profile cancer researcher Carlo Croce. The university has cleared Croce of misconduct, but disciplined him over management problems.
[Nature News]
|
|
|
|
|
Israel and the UAE have signed an agreement to promote cancer and diabetes research, in addition to a joint study on mass vitamin D deficiency in the region. [Middle East Monitor]
|
|
|
|
|
|
September 11 – 13, 2022 Lisbon, Portugal
|
|
|
|
|
|
|
Virginia Commonwealth University – Richmond, Virginia, United States
|
|
|
|
|
Boehringer Ingelheim – Vienna, Austria
|
|
|
|
|
The Chinese University of Hong Kong – Hong Kong, China
|
|
|
|
|
Children’s Medical Research Institute – Sydney, Australia
|
|
|
|
|
Université catholique de Louvain – Brussels, Belgium
|
|
|
|
|