|
|
Vol. 11.16 – 27 April, 2022
|
|
|
|
|
|
|
|
Scientists revealed a novel function of chaperone-mediated autophagy as an intrinsic regulator of glioma stem cell tumorigenic properties and highlighted its relevance in glioblastoma progression.
[Autophagy]
|
|
|
|
|
|
PUBLICATIONSRanked by the impact factor of the journal
|
|
|
|
|
|
The authors examined the mechanism by which nicotine promoted lung cancer brain metastasis. They conducted a retrospective analysis of 810 lung cancer patients with a smoking history and assessed brain metastasis.
[Oncogene]
|
|
|
|
|
|
Researchers uncovered penfluridol suppressed in vitro cell growth and in vivo tumorigenicity of various renal cell carcinoma (RCC) cell lines and enhanced the Sutent-triggered growth inhibition on clear cell RCC cell lines.
[Cell Death & Disease]
|
|
|
|
|
|
Scientists compared the signature of CD34+ stem/progenitor cells collected from chronic myeloid leukemia individuals with that of healthy donors and observed significant changes in the abundance of enzymes associated with aerobic central carbonate metabolic pathways.
[Cell Death & Disease]
|
|
|
|
|
|
SLFN11 expression was evaluated in tumor samples and characterized in circulating tumor cells (CTC) longitudinally to determine its potential role as a biomarker of response.
[British Journal of Cancer]
|
|
|
|
|
|
The authors demonstrated that the molecular mechanisms of angiopoietin-like protein 1 (ANGPTL1) in colorectal CSC progression may have provided a novel therapeutic strategy for colorectal cancer.
[Clinical Science]
|
|
|
|
|
|
Researchers reported that the voltage-gated calcium channel α2δ1 subunit-positive tumor-initiating cells of hepatocellular carcinoma specifically secreted LOX, forming a stiff extracellular matrix that was sufficient to drive the formation of tumor-initiating cells with a stiff mechanical trait.
[Carcinogenesis]
|
|
|
|
|
|
Investigators explored the effect of colorectal cancer (CRC) stem cells-derived exosomes conveying miR-17-5p on CRC.
[Cell Death Discovery]
|
|
|
|
|
|
The remarkable activity of complex 1 was observed not only in rhabdomyosarcoma cells cultured in 2D monolayers but, more importantly, also in 3D spheroids, which resembled in many aspects solid tumors and served as a promising model to mimic the in vivo situation.
[Chemico-Biological interactions]
|
|
|
|
|
|
The viability, proliferation, stemness, and migration of CD133+/CD44+, CD133−/CD44−, and colorectal cancer cells after transfection or the co-culture with exosomes were detected by MTT, colony formation, spheroid, and wound healing assays, respectively.
[Bioengineered]
|
|
|
|
|
|
|
|
|
Scientists evaluate the mechanism of cancer stemness maintenance of liver cancer stem cells (LCSCs) and discuss promising treatments for eradicating LCSCs.
[Cell Death & Disease]
|
|
|
|
|
|
|
|
Allogene Therapeutics, Inc. announced that the US FDA has granted orphan-drug designation to ALLO-605, the company’s next-generation allogenic CAR T product candidate targeting BCMA for the treatment of multiple myeloma.
[Allogene Therapeutics, Inc.]
|
|
|
|
|
|
|
|
May 12 – May 14, 2022
Yokohama, Japan
|
|
|
|
|
|
|
|
|
|
|
Johns Hopkins University – Baltimore, Maryland, United States
|
|
|
|
|
|
|
McGill University – Montreal, Quebec, Canada
|
|
|
|
|
|
|
Cyprus Cancer Research Institute – Nicosia, Cyprus
|
|
|
|
|
|
|
The University of Hong Kong – Hong Kong, China
|
|
|
|
|
|
|
Luxembourg Institute of Health – Strassen, Luxembourg
|
|
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Umbilical & Placental Cell News
