|
| Single-cell RNA sequencing, pseudotime trajectories reconstruction, and motif enrichment analysis were used, and macrophage diversity in anti-GBM cGN under tight regulation of myeloid-TLR4 was uncovered.
[Advanced Science] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Investigators revealed a robust link between cancer stemness and immunotherapy resistance and developed a promising signature, Stem.Sig, which showed increased performance in comparison to other signatures regarding immune checkpoint inhibitor response prediction.
[Genome Medicine] |
|
|
|
| Scientists studied the effectiveness of AC133-specific CAR T cells post-chemotherapy using human primary small cell lung cancer and an orthotopic xenograft mouse model.
[Cancer Letters] |
|
|
|
| Researchers examined the expression of CD6 by reconstituting T cells in 95 patients after allogeneic cell transplantation and evaluated the effects of itolizumab, an anti-CD6 monoclonal antibody, on T cell activation.
[Haematologica] |
|
|
|
| Scientists developed a T cell receptor (TRC) complex-based CAR named STAR. They reported pre-clinical and phase I clinical trial data of this T cell therapy for refractory and relapsed B cell acute lymphoblastic leukemia patients.
[American Journal of Hematology] |
|
|
|
| Mex-3 RNA Binding Family Member A (MEX3A) depletion led to decreased cell proliferation, invasion, and migration, but increased apoptosis in nasopharyngeal carcinoma cells in vitro, while inhibiting tumor growth in vivo.
[Cell Death & Disease] |
|
|
|
| Researchers suggested that the therapeutic effects of autologous hematopoietic stem cell transplantation on skin fibrosis were related to changes in molecules associated with connective tissue maintenance and inflammation in systemic sclerosis.
[Arthritis Research & Therapy] |
|
|
|
| Scientists constructed αROR1-CAR T cells and co-cultured with A549 cells with and without elevated pressure. They then measured apoptosis and cell death by flow cytometry and luciferase activity. They also measured cytokine release by ELISA.
[Scientific Reports] |
|
|
|
| Investigators developed a technique to shrink-wrap micropatterned islands of corneal endothelial cells in a basement membrane-like layer of extracellular matrix that enabled the cells to maintain their cell-cell junctions and cytoskeletal structure while in suspension.
[Communications Materials] |
|
 |
|
|
|
| That authors review the efforts into decellularization of tumors to date, which represents a new frontier in the ever evolving field of tumor tissue engineering.
[Journal of Tissue Engineering] |
|
|
|
|
| VITRAC Therapeutics, LLC initiated a Phase I/II clinical trial of VIC-1911 in combination with sirolimus and post-transplant cyclophosphamide as graft-versus-host disease prophylaxis in myeloablative allogeneic stem cell transplantation.
[VITRAC Therapeutics, LLC (BusinessWire, Inc.)] |
|
|
|
| Stem cell biotechnology company Cynata Therapeutics has started clinical trials with an initial cohort of patients in Adelaide of its patented product, aimed at treating diabetic foot ulcers.
[Cynata Therapeutics (The West Australian)] |
|
|
|
| | May 6 – 10, 2022
Portland, Oregon, United States |
|
|
|
|
|
| Johns Hopkins University School of Medicine – St. Petersburg, Florida, United States |
|
|
|
| European Molecular Biology Laboratory – Barcelona, Spain |
|
|
|
| | The University of British Columbia – Vancouver, British Columbia, Canada |
|
|
|
| | Helmholtz Munich – München, Germany |
|
|
|
| | Baylor College of Medicine – Houston, Texas, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
