 | | Vol. 23.24 – 11 July, 2022 |
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| The authors developed a novel approach for pharmacodynamic studies using transplanted, perfused human kidney organoids.
[Science Advances] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists investigated the potential impact of donor rs2204985 genotype on patient’s outcome after unrelated hematopoietic stem cell transplantation.
[Bone Marrow Transplantation] |
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| The authors described stem cells from human exfoliated deciduous teeth as gene vehicles of the thymidine kinase (TK)/ganciclovir (GCV) system against a brain metastasis model of non-small-cell lung cancer.
[Molecular Therapy-Methods & Clinical Development] |
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| Since immune cell metabolism and function are closely interconnected, researchers used flow-cytometry techniques to analyze key components and functions of the metabolic machinery in reconstituting immune cells upon high-dose chemotherapy/autologous stem cell transplantation.
[Scientific Reports] |
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| Since immune cell metabolism and function are closely interconnected, scientists used flow-cytometry techniques to analyze key components and functions of the metabolic machinery in reconstituting immune cells upon high-dose chemotherapy/autologous stem cell transplantation.
[Scientific Reports] |
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| Researchers investigated if vascular injury in immature epiphyses affected cartilage repair outcomes of matrix-associated stem cell implants.
[Scientific Reports] |
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| Scientists found that the riskof chronic graft-versus-host-disease was significantly higher in HLA-G mismatched transplant cases as compared to the HLA-G matched control group.
[HLA] |
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| Human amnion-derived mesenchymal stem cells were intravenously transplanted one day after a rat model of midthoracic spinal cord injury.
[PLoS One] |
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| In a murine heart transplantation model, scientists observed the upregulation of programmed death-ligand 1 (PD-L1) expression by FK506 in both dendritic cells and allografts.
[Scandinavian Journal of Immunology] |
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| Researchers assessed the therapeutic effects of adipose-derived mesenchymal stem cells on corticosteroid resistance in an animal model of acute exacerbation-idiopathic pulmonary fibrosis caused by bleomycin compared to pirfenidone.
[Histology and Histopathology] |
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| The authors review current delivery technologies that have been used to enable therapeutic in vivo gene editing, including viral vectors, lipid nanoparticles, and virus-like particles.
[Cell] |
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| Mogrify Limited and Astellas Pharma, Inc. announced that they have executed a collaborative research agreement on in vivo regenerative medicine approaches to address sensorineural hearing loss.
[Mogrify Limited] |
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| Vertex Pharmaceuticals Incorporated announced that the US FDA has lifted the clinical hold placed on the Phase I/II clinical trial of VX-880, an investigational stem cell-derived, fully differentiated pancreatic islet cell replacement therapy for people with type 1 diabetes with impaired hypoglycemic awareness and severe hypoglycemia.
[Vertex Pharmaceuticals Incorporated] |
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| October 3 – 5, 2022
Vancouver, British Columbia, Canada |
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| | German Cancer Research Center in the Helmholtz Association – Heidelberg, Germany |
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| | Fred Hutchinson Cancer Research Center – Seattle, Washington, United States |
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| | Georgia Institute of Technology – Atlanta, Georgia, United States |
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| | Icahn School of Medicine at Mount Sinai – New York, New York, United States |
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| | European Molecular Biology Laboratory – Barcelona, Spain |
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