Novel Immunosuppressive Effect of FK506 by Upregulation of PD-L1 via FKBP51 in Heart Transplantation

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In a murine heart transplantation model, scientists observed the upregulation of programmed death-ligand 1 (PD-L1) expression by FK506 in both dendritic cells and allografts.
[Scandinavian Journal of Immunology]
Abstract