 | | Vol. 14.16 – 26 April, 2022 |
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| The administration of bone marrow-derived mesenchymal stromal cells cultured on a 3D fiber scaffold improved bone marrow neuropathy, skin lesions, kidney function, and mortality.
[Stem Cells Translational Medicine] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors detected the survival rate, biochemical indexes, histopathology, and inflammatory chemokine levels to assess the efficacy of MSC treatment on CCl4-induced acute liver injury of C57BL/6 mice.
[Pharmacological Research] |
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| Researchers investigated the role of PPARβ/δ modulation in MSC therapeutic properties in vitro and ex vivo in an experimental model of myocardial infarction.
[Stem Cell Research & Therapy] |
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| Scientists uncovered the role of miR-21-5p shuttled by human umbilical MSC-derived exosomes, in promoting angiogenesis and osteogenesis, which may be a potential therapeutic target for osteonecrosis of the femoral head.
[Cell Death Discovery] |
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| Researchers clarified the fetal programming caused by chorioamnionitis using the gene expression profiles of umbilical cord MSCs.
[Scientific Reports] |
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| Investigators compared the therapeutic effects of human adipose MSCs and their secretome on an in vivo model of sodium iodate retinal neurodegeneration.
[Life Sciences] |
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| Researchers investigated the antifibrotic effects of bone marrow MSCs and elucidated the underlying mechanism by which BMSCs affect liver fibrosis in vitro and in vivo.
[infectious Agents and Cancer] |
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| | Investigators designed a combination of haploidentical stem cell (HSC) transplantation and MSCs for acute lymphoblastic leukemia (ALL) patients. ALL patients were given haploidentical HSCs combined with allogenic MSCs, and ALL patients without MSC infusion were included as controls.
[Bone Marrow Transplantation] |
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| An EAE model was induced in female C57BL/6 mice by injecting MOG 35–55, and researchers investigated the effect of C3H10 T1/2, which are mouse-derived MSCs, cell transplantation for the EAE model after downregulation of B7-H4 in vivo.
[Neurotoxicity Research] |
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| The strategy of MSCs enrichment combined with gelatin sponge by selective cell retention technology provided a rapid, simple, and effective method for cell concentration and cell-carrier combination.
[Frontiers in Bioscience-Landmark] |
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| Thus far, therapy with MSCs appears to be safe for use in humans, as no severe adverse events directly related to the therapy were reported.
[Epilepsia] |
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| The authors provide an unbiased review of recent advances in MSCs for the treatment of diabetic kidney disease (DKD) in the last decade from the perspectives of the pathogenesis of DKD, biological characteristics of MSCs, and different molecular and signaling pathways.
[Molecular and Cellular Biochemistry] |
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| The Cancer Prevention and Research Institute of Texas awarded a four-year, $1.34 million grant to C. Patrick Reynolds, director for the School of Medicine Cancer Center at the Texas Tech University Health Sciences Center, for his investigation into updating the clinical risk stratification scale for neuroblastoma and rhabdomyosarcoma.
[Texas Tech University (EurekAlert!)] |
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| September 19 – 20, 2022
Vejle, Denmark |
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| | Francis Crick Institute – London, United Kingdom |
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| | Wayne State University – Detroit, Michigan, United States |
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| | Johns Hopkins University – Baltimore, Maryland, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | Novo Nordisk – Fremont, California, United States |
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