Depletion of B7-H4 from C3H10 T1/2 Mesenchymal Stem Cells Attenuates their Immunomodulatory Therapy in Experimental Autoimmune Encephalomyelitis Mice

An EAE model was induced in female C57BL/6 mice by injecting MOG 35–55, and researchers investigated the effect of C3H10 T1/2, which are mouse-derived MSCs, cell transplantation for the EAE model after downregulation of B7-H4 in vivo.