 | | Vol. 14.35 – 6 September, 2022 |
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| The authors hypothesized that the cholinergic anti-inflammatory pathway may be involved in the therapeutic mechanisms by which MSCs mitigate acute respiratory distress syndrome.
[Signal Transduction and Targeted Therapy] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Using an adipogenic differentiation screen, researchers identified IFNγ and TGFβ as key inhibitors of primary human visceral adipose tissue-resident multipotent-MSC differentiation.
[NPJ Regenerative Medicine] |
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| Investigators determined the role and regulatory mechanisms of ubiquitin-like with PHD and ring finger domains 1 (UHRF1) in rendering osteosarcoma cells more aggressive.
[Oncogenesis] |
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| Scientists aimed to determine the roles of the β-catenin/Oct4 signaling axis in the regulation of long-term survival and angiogenesis of peripheral blood MSCs.
[Experimental & Molecular Medicine] |
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| Researchers performed differential expression analysis of miRNAs between human bone MSCs and human dental pulp stem cells to identify osteogenic differentiation-related miRNAs.
[Stem Cell Research & Therapy] |
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| Investigators showed that bone marrow microenvironment (BMM)-deficiency of pleckstrin homology domain family M member 1 accelerated murine BCR-ABL1+ B-cell acute lymphoblastic leukemia via regulation of the cargo of small extracellular vesicles released by BMM-derived MSC.
[Blood Advances] |
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| Scientists attempted to generate a zone of calcified cartilage using equine MSCs as the single source of cells and collagen as the scaffolding material.
[Biomedical Materials] |
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| Researchers demonstrated a novel way for a comprehensive cardiac repair achieved by the sutureless transplantation of highly integrable in vivo priming bone marrow MSC sheet based on the utilization of a highly aligned thermoresponsive nanofiber membrane.
[Biofabrication] |
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| MSCs effectively homed to the corpus callosum area, were able to improve motor coordination, and to promote myelin recovery in the intermittent cuprizone.
[Neurotoxicity Research] |
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| The authors summarize findings published on the use of adipose-derived stromal cells in the dermato-oncological setting, with the majority of data being available for melanoma.
[Stem Cells and Development] |
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| Immutep Limited announced it has signed a Material Transfer Agreement with the Maria Skłodowska-Curie National Research Institute of Oncology in Warsaw, Poland to enable an investigator-initiated open-label Phase II clinical trial.
[Immutep Limited] |
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| November 17 – 18, 2022
Lisbon, Portugal |
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| | Icahn School of Medicine at Mount Sinai – New York City, New York, United States |
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| | University of Copenhagen – Copenhagen, Denmark |
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| | STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada |
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| | Oklahoma Medical Research Foundation – Oklahoma City, Oklahoma, United States |
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| | Shenzhen Institute of Advanced Technology – Shenzhen, China |
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