 | | Vol. 14.36 – 13 September, 2022 |
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| Investigators developed an electronically modulated metal oxide via Mn atom substitutions in Co3O4 nanocrystalline for highly efficient and multifaceted catalytic reactive oxygen species-scavenging to reverse the fates of MSCs in oxidative stress microenvironments.
[Advanced Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers evaluated the antitumoral activity of propranolol using different in vitro and in vivo osteosarcoma preclinical models, alone or in addition to chemotherapy.
[Scientific Reports] |
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| Scientists hypothesized that autologous MSC recellularization of bovine pericardium would result in reduced pro-inflammatory cytokine production equivalent to autologous human pericardium.
[Xenotransplantation] |
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| Via gain- and loss-of-function experiments, the authors demonstrated that sprouty protein 4 (SPRY4) promoted human adipose-derived MSC adipogenesis both in vitro and in vivo.
[Adipocyte] |
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| Researchers determined the effect of transforming growth factor-beta 1 (TGF-β1) and –β3 on the MSCs chondrogenic differentiation on the poly (vinyl alcohol)-chitosan-poly (ethylene glycol) (PVA-NOCC-PEG) scaffold, compared to that of monolayer and pellet cultures.
[Tissue Engineering Part C-Methods] |
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| Thawed cells were assessed for their morphology, phenotypic marker expression, viability, apoptosis level, metabolic activity, proliferation, and osteogenic and adipogenic differentiation.
[Biopreservation and Biobanking] |
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| The authors assessed the mechanisms of how intrahepatic co-infusion of human alpha-1 antitrypsin-engineered mesenchymal stromal cells improved survival of human islet grafts post transplantation.
[Diabetes] |
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| Scientists constructed extra-hepatic functional islet tissue by transferring the 3D beta cells and GFP labeled MSCs MSC sheets to the subcutaneous site of rats with STZ-induced diabetes
[Tissue and Cell] |
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| Investigators aimed to compare the Silymarin, as traditional treatment with MSC conditioned medium, as a novel strategy, both with therapeutic potentialities in term of liver failure treatment.
[Molecular Biology Reports] |
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| The authors review the immunomodulatory features of MSC, besides the current understanding of different sources of MSCs, in the angiogenic treatment of critical limb ischemia subjects and their potential applications as therapeutic agents.
[Stem Cell Research & Therapy] |
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| IMAC Holdings, Inc. announced it has completed the third cohort of its Phase I clinical trial for its investigational compound utilizing umbilical cord-derived allogenic MSCs for the treatment of bradykinesia due to Parkinson’s disease.
[IMAC Holdings, Inc. (GlobeNewswire, Inc.)] |
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| October 16 – 21, 2022
Ventura, California, United States |
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| | Karolinska Institutet – Flemingsberg, Sweden |
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| | Icahn School of Medicine at Mount Sinai – New York City, New York, United States |
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| | STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada |
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| | Gunderson Health System – La Crosse, Wisconsin, United States |
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| | Oklahoma Medical Research Foundation – Oklahoma City, Oklahoma, United States |
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