 | | Vol. 7.24 – 11 July, 2022 |
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| To identify candidate therapeutics, scientists developed an in vitro dilated cardiomyopathy model using induced pluripotent stem cell-derived cardiomyocytes deficient in B-cell lymphoma 2-associated athanogene 3 (BAG3).
[Science Translational Medicine] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers identified the phenotype of SNTA1-deficiency using human cardiomyocytes.
[Stem Cell Research & Therapy] |
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| The authors investigated how miRNAs regulated myocardial cell pyroptosis in diabetic cardiomyopathy development.
[Toxicology] |
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| Researchers demonstrated that modulation of the epigenetic regulator gene p63 improved the efficiency of human cell cardio-differentiation.
[Scientific Reports] |
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| In cultured C2C12 myocytes, lenvatinib inhibited carnitine/organic cation transporter 2 expression in a dose-dependent manner at the protein level.
[Toxicology Letters] |
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| Researchers assessed mitochondrial content and capacity in fully differentiated CD56+ human skeletal muscle cells from lean active and sedentary individuals with obesity at baseline.
[American Journal of Physiology-Cell Physiology] |
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| Investigators revealed that miR-18 inhibited the differentiation of bovine skeletal muscle-derived satellite cells, whereas a miR-18 inhibitor significantly promoted cell differentiation.
[Journal of Animal Science] |
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| Scientists found that macrophages and their extracellular vehicles promoted vascular smooth muscle cell (VSMC) osteogenic differentiation and upregulated miR-32 expression in VSMCs.
[Journal of Translational Medicine] |
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| Researchers investigated the anti-inflammatory effect of two purine analogues, MK118 bearing a nitrate ester moiety and the methyl-substituted analogue MK196 in aortic smooth muscle cells, with emphasis on IL-1β release.
[European Journal of Pharmacology] |
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| The authors investigated the effect of glycolaldehyde on the expression of adhesion molecules in the mouse vascular smooth muscle cell line, MOVAS-1.
[PLoS One] |
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| Scientists examined the possible cross-talk between angiotensin II and hyperglycemia on vascular smooth muscle cell senescence, and the roles of AT2 receptor agonist, compound 21 on it.
[American Journal of Hypertension] |
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| The authors summarize the structural and functional differences between human pluripotent stem cell-derived cardiomyocytes and mature cardiomyocytes, and introduced various methods to induce cardiomyocyte maturation.
[Stem Cell Reviews and Reports] |
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| Investigators discuss six specific examples of differences in muscle satellite cell dynamics between regeneration and hypertrophy processes.
[Skeletal Muscle] |
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| RetinalGeniXâ„¢ Technologies, Inc. announced the acquisition of DNA/GPS Inc. RetinalGeniX has acquired the rights to the platform technology designed by Dr. Perich, which allows healthcare providers to give diagnoses of systemic diseases including heart disease, Alzheimer’s, dementia, Parkinson’s and more.
[RetinalGeniX Technologies, Inc.(GlobeNewswire, Inc.)] |
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| December 3 – 7, 2022
Washington, DC, United States |
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| | King’s College London – London, England, United Kingdom |
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| | National University of Ireland Galway – Galway, Ireland |
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| | The Chinese University of Hong Kong – Hong Kong, China |
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| | The University of Tennessee Health Science Center – Memphis, Tennessee, United States |
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| | Duke University – Durham, North Carolina, United States |
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