 | | Vol. 7.31 – 12 September, 2022 |
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| Scientists unraveled a fundamental role for exercise-responsive cytokines on skeletal muscle development and growth in individuals with normal glucose tolerance or type 2 diabetes.
[Science Advances] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators showed that FUN14 domain–containing 2 (FUNDC2), a highly conserved and ubiquitously expressed mitochondrial outer membrane protein, regulated ferroptosis and contributed to doxorubicin–induced cardiomyopathy.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| Researchers evaluated the effect of space microgravity on differentiation of human induced pluripotent stem cell (hiPSC)-derived cardiac progenitors compared with 1G cultures on the International Space Station (ISS). Cryopreserved 3D cardiac progenitors were cultured for three weeks on the ISS.
[Stem Cell Reports] |
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| | Scientists studied the underlying mechanisms of UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase myopathy (GNEM) using a patient-derived induced pluripotent stem cell (iPSC) model.
[NPJ Regenerative Medicine] |
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| The authors demonstrated “cell sheet-based meat”: scaffold-free cell-based meat using cell sheet technology and characterized its texture and nutrients.
[NPJ Food Science] |
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| Researchers investigated the evolutionary origins and function of membrane-coalescing agents Myomaker and Myomixer in various groups of chordates.
[Science Advances] |
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| Investigators found that BAF60c was downregulated in human and mouse abdominal aortic aneurysm tissues, with primary staining to vascular smooth muscle cells, confirmed by single-cell RNA-sequencing.
[Journal of Clinical Investigation] |
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| Cellular communication between the different cell types of the heart is essential for cardiac repair and regeneration and can be targeted by various approaches, which the authors term “coalition to heal.”
[Science] |
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| Post-acute sequelae of SARS-CoV-2 represents a formidable challenge for health care systems and dissecting pathogenetic mechanisms may pave the way to targeted preventive and therapeutic approaches.
[Cell Death & Differentiation] |
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| Scientists summarize the available state of knowledge surrounding the physiological mechanisms underlying cell maturation in several key tissues.
[NPJ Regenerative Medicine] |
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| Pluri, Inc. announced that a €7.5 million non-dilutive grant from the European Union’s Horizon Europe program has been awarded to Advanced PeRsOnalized Therapies for Osteoarthritis (PROTO), an international collaboration led by Charité, Berlin Institute of Health Center for Regenerative Therapies.
[Pluri, Inc. (GlobeNewswire, Inc.)] |
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| February 9 – 12, 2022
Cancun, Mexico |
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| | USI – Bellinzona, Switzerland |
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| | European Molecular Biology Laboratory – Heidelberg, Germany |
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| | The Ohio State University – Columbus, Ohio, United States |
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| | University of British Columbia – Vancouver, British Columbia, Canada |
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| | Duke University – Durham, North Carolina, United States |
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