Distinctive Exercise-Induced Inflammatory Response and Exerkine Induction in Skeletal Muscle of People with Type 2 Diabetes

Mechanistic insights into the molecular events by which exercise enhances the skeletal muscle phenotype were lacking, particularly in the context of type 2 diabetes. Scientists unraveled a fundamental role for exercise-responsive cytokines (exerkines) on skeletal muscle development and growth in individuals with normal glucose tolerance or type 2 diabetes.