 | | Vol. 3.35 – 15 September, 2022 |
| |
|
|
| Knockout in genome-edited cerebral organoids, scientists found that the modern human variant, human Transketolase-like 1 (TKTL1), but not the Neanderthal variant, increases the abundance of basal radial glia but not that of intermediate progenitors
[Science] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| ARHGAP11B expression in chimpanzee cerebral organoids doubled basal progenitor levels, the class of cortical progenitors with a key role in neocortex expansion.
[EMBO Reports] |
|
|
|
| The authors examined the potential of mouse epiblast stem cells cultured in media containing Wnt pathway inhibitors as a starting point for directed differentiation.
[Development] |
|
|
|
| Investigators compared the cell composition of cerebral organoids (COs) at different culture time and explored the cell types, cell ratios, and volume size of COs at 85 days.
[Acta Pharmacologica Sinica] |
|
|
|
| Scientists reported a pivotal role of fused in sarcoma (FUS) in regulating the human cortical brain and spinal cord development via the human iPSCs-derived organoids.
[Molecular and Cellular Neuroscience] |
|
|
|
| Tumor tissues were collected, and OCT4, SOX2, and NANOG expressions were assessed by immunohistochemistry staining to investigate the association of stemness markers with overall survival.
[BMC Cancer] |
|
|
|
| By using cerebral organoids, a self-organized, functional and multicellular 3D structure that resemble the brain, scientists were able to identify μ, δ, and κ opioid receptors at different stages of maturation.
[Stem Cells and Development] |
|
|
|
| The authors generated retinal organoids using iPSCs from renal epithelial cells obtained from four children with AIPL1 nonsense mutations.
[Cell Reports Methods] |
|
|
|
| Researchers developed a technology to make forebrain organoids from feeder-free induced PSCs by regulating a FGF2 concentration.
[Cell Reports Methods] |
|
 |
|
|
|
| Scientists provide an overview of the current understanding of intestinal epithelial self-renewal during homeostasis and regeneration, and provide a perspective for future organoid medicine.
[Current Opinion in Genetics & Development] |
|
|
|
|
| Researchers at the Johns Hopkins Bloomberg School of Public Health have been awarded a $11.7 million, five-year Autism Center of Excellence grant from the National Institutes of Health.
[Johns Hopkins] |
|
|
|
|
| November 1- 6
Orlando, Florida, United States |
|
|
|
|
|
| | University of California Santa Cruz – Santa Cruz, California, United States |
|
|
|
| | European Molecular Biology Laboratory – Barcelona, Spain |
|
|
|
| | USI – Bellinzona, Switzerland |
|
|
|
| | Max Delbrück Center for Molecular Medicine – Berlin, Germany |
|
|
|
| | Lewis Katz School of Medicine, Temple University – Philadelphia, Pennsylvania, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
