PLGA-Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NFκB, Cancer Stem Cells and Targets Glioblastoma in Vitro and in Vivo

The in vitro anti-glioblastoma (GBM) stem cell activity of disulfiram (DS) and in vivo anti-GBM efficacy of poly lactic-co-glycolic acid nanoparticle-encapsulated DS were examined.