Phenotypic Composition of Commercial Anti-CD19 CAR-T Cells Affects In Vivo Expansion and Disease Response in Large B Cell Lymphoma Patients

Residual cells obtained after washing 61 anti-CD19 CAR-T product bags were analyzed to identify tisagenlecleucel/Tisa-cel and axicabtagene ciloleucel/Axi-cel phenotypic features associated with post-infusion CAR-T cell in vivo expansion and with response and survival.