HDAC5, Negatively Regulated by miR-148a-3p, Promotes Colon Cancer Cell Migration

To clarify the role of Class IIa Histone deacetylases (HDACs) in the metastasis of colon adenocarcinoma, investigators used the Class IIa HDAC inhibitor TMP269 and found that it effectively inhibited the migration ability of colon adenocarcinoma cells.