Targeting Epidermal Growth Factor Receptor in Paclitaxel-Resistant Human Breast and Lung Cancer Cells with Upregulated Glucose-6-Phosphate Dehydrogenase

EGFR signaling-mediated glucose-6-phosphate dehydrogenase (G6PD) expression plays a pivotal role in paclitaxel resistance, highlighting the potential of targeting EGFR to overcome paclitaxel resistance in triple-negative breast cancer and NSCLC cells overexpressing G6PD.