RNF216 Alleviates Radiation-Induced Apoptosis and DNA Damage Through Regulating Ubiquitination-Mediated Degradation of p53 in Glioblastoma

Researchers compared the ring finger protein 216 (RNF216) expression in glioblastoma (GBM) tissues and normal peritumoral tissues and examined the effects of RNF216 overexpression/knockdown on tumorigenesis, radioresistance, and the p53 pathway in GBM.