TXN Inhibitor Impedes Radioresistance of Colorectal Cancer Cells with Decreased ALDH1L2 Expression via TXN/NF-κB Signaling Pathway

Bioinformatic analysis, in vitro, and in vivo experiments revealed that aldehyde dehydrogenase 1 family member L1 (ALDH1L1) was a radiation-related gene, and a decrease in its expression induced radioresistance in colorectal cancer cells by inhibiting ROS-mediated apoptosis.