Long Noncoding RNA ZBTB40-IT1 Regulates Bone Mass by Directing the Differentiation of Human Bone Marrow Mesenchymal Stromal Cells via the microRNA-514a-3p/FOXO4 Axis

Researchers clarified the mechanism of long noncoding RNA ZBTB40-IT1 in directing human bone marrow-derived MSC (hBMSC) differentiation. hBMSCs underwent osteogenic and adipogenic induction, and an osteoporosis mouse model was established via ovariectomy