Identification of Biomarkers for Immunotherapy Response in Prostate Cancer and Potential Drugs to Alleviate Immunosuppression
Co-expression networks were constructed and survival analysis was applied to hub genes. Drug candidates to alleviate immunosuppression were filtered in prostate cancer using GSEA based on hub genes.
[Haematologica] Myeloid-derived suppressor cells (MDSCs) populations were evaluated in acquired aplastic anemia in which aberrant immune mechanisms contributed to bone marrow destruction.
[Cell Death & Disease] To investigate the effect of ellagic acid (EA) on benign prostate hyperplasia, scientists used EA, a phytochemical abundant in fruits and vegetables, to treat testosterone propionate-induced BPH rats and RWPE-1 human prostate epithelial cells.