PU.1-Driven Th9 Cells Promote Colorectal Cancer in Experimental Colitis Models through IL-6 Effects in Intestinal Epithelial Cells

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Colorectal cancer patient samples and samples from AOM/DSS treated mice were analyzed for expression of IL-9, CD3 and PU.1 by FACS analysis and immunohistochemistry.
[Journal of Crohn’s and Colitis]
Abstract