Targeting NAD Metabolism Regulates Extracellular Adenosine Levels to Improve the Cytotoxicity of CD8⁺ Effector T Cells in the Tumor Microenvironment of Gastric Cancer

Investigators targeted nicotinamide phosphoribosyltransferase, a rate-limiting enzyme in the NAD+ synthesis salvage pathway, to observe its effect in the immune microenvironment.