PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma

By
lbeveridge
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0
340
Mechanistically, interleukin-1β derived from IFN-γ-polarized tumor macrophages triggered PIM2 expression in cancer cells via the p38 MAPK/Erk and NF-κB signaling pathways.
[Cancer Research]
Abstract