EGFR Ligand Shifts the Role of EGFR from Oncogene to Tumor Suppressor in EGFR-Amplified Glioblastoma by Suppressing Invasion through BIN3 Upregulation

Investigators demonstrated a new tumor-suppressive function of epidermal growth factor receptor (EGFR) in EGFR-amplified glioblastomas regulated by EGFR ligands.