CD9 Mediates the Uptake of Extracellular Vesicles From Cancer-Associated Fibroblasts That Promote Pancreatic Cancer Cell Aggressiveness

Scientists demonstrated that blocking either CD9 or p38 MAPK signaling impaired CD9+ annexin A6 extracellular vesicle–induced cell migration and epithelial-to-mesenchymal transition in PDAC cells.