Exosomes Derived from Myeloid-Derived Suppressor Cells Facilitate Castration-Resistant Prostate Cancer Progression via S100A9/circMID1/miR-506-3p/MID1
CircRNA expression profiles in prostate cancer cells treated with Myeloid-derived suppressor cells- exosomes and control cells were investigated using a circRNA microarray.
[Signal Transduction and Targeted Therapy] Scientists provide an update on recent clinical applications using either human pluripotent stem cells or mesenchymal stem cells derived from bone marrow, adipose tissue, or the umbilical cord for the treatment of human diseases.
[Scientific Reports] The authors suggested a novel strategy to treat triple negative breast cancer (TNBC) using mesenchymal stem cell-derived extracellular vesicles to transform the behaviors and cellular communication of TNBC cells with other non-cancer cells related to tumorigenesis and metastasis.
[Cancer Discovery] Researchers combined CAR T19 with the FDA-approved BCL-2-inhibitor, venetoclax, and demonstrated in vivo synergy in venetoclax-sensitive non-Hodgkin lymphoma.