Early B Cell Factor 4 Modulates FAS-Mediated Apoptosis and Promotes Cytotoxic Function in Human Immune Cells

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Researchers identified early B cell factor 4 (EBF4), a little-studied member of the EBF family of transcription factors, in a whole-genome CRISPR screen for regulators of Fas/APO-1/CD95-mediated T cell death.
[Proceedings of the National Academy of Sciences of the United States of America]
Abstract