αvβ3 Integrin-Specific Exosomes Engineered with Cyclopeptide for Targeted Delivery of Triptolide against Malignant Melanoma

Researchers applied exosome derived from human umbilical cord MSCs (hUCMSCs) and engineered them exogenously with a cyclic peptide, arginine-glycine-aspartate to encapsulate triptolide to establish a bionic-targeted drug delivery system, achieving synergism and toxicity reduction.