Efficacy of JAK 1/2 Inhibition in Murine Immune Bone Marrow Failure

After infusion of lymph node (LN) cells mismatched at the major histocompatibility complex, RUX, administered as a food additive, attenuated bone marrow hypoplasia, ameliorated peripheral blood pancytopenia, preserved hematopoietic progenitors, and prevented mortality, when used either prophylactically or therapeutically.