SIRPα Maintains Macrophage Homeostasis by Interacting with PTK2B Kinase in Mycobacterium tuberculosis Infection and Through Autophagy and Necroptosis

Meta-analysis combined with subsequent qRT-PCR, western-blotting and flow cytometry assay were used to detect SIRPα expression in pulmonary tuberculosis patients. Cell-based assays were used to explore the regulation of macrophage function by SIRPα.