Activation of the Kynurenine–Aryl Hydrocarbon Receptor Axis Impairs the Chondrogenic and Chondroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stromal Cells in Osteoarthritis Rats

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The effects of kynurenine, one of the most important metabolites of tryptophan, were evaluated on the chondrogenic and chondroprotective effects of human umbilical cord-derived MSCs.
[Human Cell]
Abstract