TrkC-Mediated Inhibition of DJ-1 Degradation Is Essential for Direct Regulation of Pathogenesis of Hepatocellular Carcinoma

Researchers demonstrated the possible association between upregulation of TrkC and acquisition of cancer stem cells traits or chemoresistance in HCC. They showed that upregulation of TrkC was closely associated with the survival and progression of HCC in vivo and in vitro.