NewslettersImmune Regulation NewsAntigen-Specific Depletion of CD4+ T Cells by CAR T Cells Reveals Distinct Roles of Higher- and Lower-Affinity TCRs during AutoimmunityBy lbeveridge - October 14, 20220103Integration of improvements in CAR engineering with TCR repertoire analysis was critical for interrogating in vivo the role of TCR affinity in autoimmunity.[Science Immunology]Full Article