Mesenchymal Stem Cells Exosomal Let-7a-5p Improve Autophagic Flux and Alleviate Liver Injury in Acute-on-Chronic Liver Failure by Promoting Nuclear Expression of TFEB

Scientists showed that MSCs restored the impaired autophagic flux and alleviated liver injuries in acute-on-chronic liver failure mice, but these effects were abolished when autophago-lysosomal maturation was inhibited by leupeptin.