Regulatory T Cell-Derived Interleukin-15 Promotes the Diversity of Immunological Memory

Using a lymphocytic choriomeningitis virus (LCMV) Armstrong infection mouse model, we found that Treg cell-derived interleukin (IL)-15 is required for long-term maintenance of the KLRG1+IL-7Rα−CD62L− terminal effector memory CD8+ T (tTEM) cell subset