ABO Gene Editing for the Conversion of Blood Type A to Universal Type O in Rh_null Donor-Derived Human-Induced Pluripotent Stem Cells

Researchers presented a CRISPR/Cas9-mediated ABO gene edition strategy for the conversion of blood type A to universal type O, which they had applied to an Rhnull donor-derived hiPSC line, originally carrying blood group A.