Therapeutic Function of a Novel Rat Induced Pluripotent Stem Cell Line in a 6-OHDA-Induced Rat Model of Parkinson’s Disease

Green fluorescent protein+/iPS‑like colony generation was facilitated by the small molecules CHIR99021 and RepSox during lentivirus‑mediated reprogramming of six transcription factors in rat embryonic fibroblasts. The generation of iPSCs was detected by reverse transcription‑PCR, immunofluorescence, and western blot analysis.