Administration of Broadly Neutralizing Anti-HIV-1 Antibodies at ART Initiation Maintains Long-Term CD8+ T Cell Immunity

Using the activation-induced marker assay and interferon-γ release, scientists observed that frequencies of Pol- and Gag-specific CD8+ T cells, as well as Gag-induced interferon-γ responses, were significantly higher among individuals that received adjunctive 3BNC117 compared to ART-alone at 3 and 12 months after starting ART.