NewslettersHematopoiesis NewsMyeloid-Derived Itaconate Suppresses Cytotoxic CD8+ T Cells and Promotes Tumour GrowthBy Jamie Kang - November 14, 20220627Investigators discovered that myeloid-derived suppressor cells secreted itaconate that can be taken up by CD8+ T cells and suppressed their proliferation, cytokine production, and cytolytic activity.[Nature Metabolism]Abstract