Co-Infection of Porcine Deltacoronavirus and Porcine Epidemic Diarrhea Virus Induces Early TRAF6-Mediated NF-κB and IRF7 Signaling Pathways through TLRs

The authors investigated the gene expression levels of pattern recognition receptors, downstream inflammatory signaling pathway molecules, and associated cytokines on the intestinal mucosa of neonatal piglets either infected with a single- or co-infected with porcine deltacoronavirus and porcine epidemic diarrhea virus using real-time PCR.