Differential Integrated Stress Response and Asparagine Production Drive Symbiosis and Therapy Resistance of Pancreatic Adenocarcinoma Cells

[Prostate Cancer Foundation] The Prostate Cancer Foundation announced four inaugural Class of 2022 TACTICAL Award recipients. This $30 million program will support cross-disciplinary pioneering research toward the goal of developing 21st Century therapies for the most life-threatening form of prostate cancer.

[Molecular Cell] Scientists reported that PALI1 was upregulated in advanced prostate cancer and competed with JARID2 for binding to the polycomb repressive complex 2 core subunit SUZ12.

[Nature Communications] Researchers reported high levels of androgen receptor chromatin binding heterogeneity in human primary prostate tumors, that overlapped with heterogeneity observed in healthy prostate epithelium.