Effects of hsa-miR-9-3p and hsa-miR-9-5p on Topoisomerase IIβ Expression in Human Leukemia K562 Cells with Acquired Resistance to Etoposide

Using microRNA (miRNA) sequencing and quantitative PCR, researchers found that both miR-9-3p and miR-9-5p were overexpressed in the etoposide resistant K562 clonal subline, K/VP.5 compared with K562 cells.