Plasma Exosomes Confer Hypoxic Pulmonary Hypertension by Transferring LOX-1 Cargo to Trigger Phenotypic Switching of Pulmonary Artery Smooth Muscle Cells

Researchers generated proof that plasma-derived exosomes confer pulmonary hypertension by delivering lipoprotein receptor-1 (LOX-1) into pulmonary artery smooth muscle cells.