Determining Epigenetic Memory in Kidney Proximal Tubule Cell Derived Induced Pluripotent Stem Cells Using a Quadruple Transgenic Reprogrammable Mouse

Scientists reprogrammed proximal tubule cells and tail tip fibroblasts from a reprogrammable mouse to iPSCs and differentiated the iPSCs to renal progenitors to understand if epigenetic memory played a role in renal differentiation.