Knockdown of Membrane-Bound Complement Regulatory Proteins Suppresses Colon Cancer Growth in Mice through Inducing Tumor Cell Apoptosis

Membrane-bound complement regulatory proteins (mCRPs) expression in human colon cancer cells were upregulated by STAT3/STAT6/p38 MAPK signaling and mCRPs knockdown reduced colon cancer growth in mice through inducing tumor cell apoptosis.