Desloratadine, an FDA-Approved Cationic Amphiphilic Drug, Inhibits SARS-CoV-2 Infection in Cell Culture and Primary Human Nasal Epithelial Cells by Blocking Viral Entry

Investigators assessed the anti-SARS-CoV-2 effectiveness of 8 FDA-approved cationic amphiphilic drugs on human nasal epithelial cells and revealed their antiviral mode of action.