CD34^dim Cells Identified as Pluripotent Stem Cell-Derived Definitive Hemogenic Endothelium Purified Using Bone Morphogenetic Protein 4

Scientists identified and validated a CD34dim subpopulation with hemogenic potential. They also purified CD34 cells with a CXCR4−CD73−phenotype as a definitive hemogenic endothelium population that generated HSCs and lymphocytes.