NewslettersESC & iPSC NewsA Congenital Hydrocephalus-Causing Mutation in Trim71 Induces Stem Cell Defects via Inhibiting Lsd1 mRNA TranslationBy Noshin Noorjahan - January 4, 20230308Using mESCs as a model, scientists revealed that the mouse R783H mutation (R796H in human) altered Trim71’s mRNA substrate specificity and led to accelerated stem-cell differentiation and neural lineage commitment.[Embo Reports]AbstractGraphical Abstract