TPX2 Prompts Mitotic Survival via the Induction of BCL2L1 through YAP1 Protein Stabilization in Human Embryonic Stem Cells

Researchers demonstrated that the expression of targeting protein for Xklp2 (TPX2) led to BCL2L1 induction and consequent survival traits under mitotic stress in isogenic pairs of hESCs and iPSCs with normal and 20q11.21 copy number variations.